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对1988年7月1994年8月间接受放疗的67例晚期口腔颌面部鳞癌术后复发患者进行评价。结果:放疗后完全缓解为29.9%(20/67),部分缓解为40.3%(27/67),无效为29.9%(20/67);总有效率为70.1%(47/67);放疗后已死亡50例,中位生存期16月;生存率:1年为56.7%(38/67),2年为20.9%(14/67),3年为4.5%(3/67);远处转移率31.3%,放疗并发症率11.9%。分析表明,照射50Gy以上患者的疗效显著优于50Gy以下者(P<0.01);超分割连续放射的疗效优于分段放射(P<0.05)。本文对复发患者的放疗反指证及提高疗效的多模式治疗进行了讨论。
The 67 patients with advanced oral and maxillofacial squamous cell carcinoma who received radiotherapy between July 1988 and August 1994 were evaluated. Results: The complete remission after radiotherapy was 29.9% (20/67), partial remission was 40.3% (27/67), and the invalidity was 29.9% (20/67); the total effective rate was 70.1% (47/67); 50 cases died after radiotherapy and the median survival period was 16 months; the survival rate was 56.7% (38/67) in 1 year and 20.9% (14/67) in 2 years, 3 The annual rate was 4.5% (3/67); the distant metastasis rate was 31.3%, and the radiotherapy complication rate was 11.9%. The analysis showed that the effect of patients with 50Gy or above was significantly better than those with 50Gy or less (P<0.01); the effect of hyperfractionated continuous radiation was superior to segmented radiation (P<0.05). This article discusses the recurrence of patients with radiotherapy anti-indication and multimodal therapy to improve efficacy.