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变应性接触性皮炎(ACD)和异位性皮炎都是湿疹皮炎类的代表性疾病,尤其是其中的ACD,可以作为研究湿疹反应的模式。本文就以ACD为重点,介绍有关湿疹反应及其免疫现象的新观点。一、变应性接触性皮炎(ACD) ACD是第Ⅳ型变态反应引起的免疫性疾病,与结核菌素反应和移植排斥反应同属一种免疫反应,但具有如下特点,即变应原是简单化学物质(分子量小于1,000),在免疫学上称为半抗原;可经皮肤侵入体内,并以皮肤为变态反应的靶器官,在病理组织学上
Allergic contact dermatitis (ACD) and atopic dermatitis are all representative diseases of eczema dermatitis, especially ACD, which can be used as a model to study the eczema response. This article focuses on the ACD, introducing new perspectives on the eczema response and its immunization. First, the allergic contact dermatitis (ACD) ACD is a type IV allergic reaction caused by immune disease, and tuberculin reaction and transplant rejection belong to the same immune response, but has the following characteristics, namely the allergen is simple Chemical substances (molecular weight of less than 1,000), immunologically known as haptens; penetrated the body through the skin, and the skin as the target organ of the allergy, histopathologically