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鉴于乳酸脱氢酶、硷性磷酸酶、酸性磷酸酶、5’-核苷酸磷酸二酯酶以及芳香族硫酸酯酶的同工酶等的生化特性与诊断价值本刊已有过系统的综述资料,本文只对其它常用的或有肯定诊断价值的同工酶进行讨论。乙醇脱氢酶(EC.1.1.1,ADH) 现已证实肝细胞中含有两型ADH同工酶:位于胞液(上清或可溶部分)的S-ADH,占肝细胞总活性的80%,对正-戊醇(Am)和乙醇(Et)两种作用物的反应相似,Am/Et比
In view of the biochemical characteristics and diagnostic value of lactate dehydrogenase, alkaline phosphatase, acid phosphatase, 5’-nucleotide phosphodiesterase and aromatic sulfatase isoenzymes, etc., has been systematically reviewed Data, this article only discusses other common or have certain diagnostic value of isoenzyme. Alcohol dehydrogenase (EC.1.1.1, ADH) It has been demonstrated that hepatocytes contain two types of ADH isoenzymes: S-ADH located in the cytosol (supernatant or soluble fraction), accounting for 80% of the total hepatocyte activity %, The reaction of n-amyl alcohol (Am) and ethanol (Et) was similar, Am / Et ratio