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苯甲氧基乙酸(Pheny lmethoxy aceticacid)[1]及其酯已有近百年的合成历史,由[1]及其衍生物合成了众多的具有生理活性的杂环化合物。姜贵吉等注意到此类化合物符合植物生长激素的化学结构条件。近年来Abraham等发现化合物[1]类具有很强的抗镰形化活性(antisickling activity)和抗凝聚活性(antigelling activity),用于治疗镰状细胞性贫血症。Randall等发现化合物[1]具有羟基酸氧化酶(GAO)抑制作用,其酯类还具有抗胆
Pheny lmethoxy acetic acid (1) and its esters have been synthesized for nearly one hundred years. A large number of physiologically active heterocyclic compounds have been synthesized from [1] and its derivatives. Jiang Guiji and so noticed that these compounds meet the plant growth hormone chemical structure conditions. In recent years, Abraham et al. Have found that compounds [1] have strong anti-tickling activity and antigelling activity for the treatment of sickle-cell anemia. Randall et al. [1] found that compound [1] has the inhibition of hydroxy acid oxidase (GAO), and its esters also have anti-gall