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白血病时由于异常造血细胞克隆的恶性增殖,使巨核系统处于抑制状态,导致巨核细胞在瑞氏染色时辩认困难,故对其了解较少。我们应用对巨核细胞特异的GPⅡb/Ⅲa单克降抗体(CD_(41))APAAP免疫酶标法观察了40例白血病患者的骨髓及部分外周血中的巨核细胞。结果如下:
In leukemia, due to the malignant proliferation of abnormal hematopoietic cell clones, the megakaryocyte system is in an inhibitory state, resulting in difficulty in recognizing megakaryocytes in Wright’s staining, and therefore little is known about it. We used megakaryocyte-specific GPIIb/IIIa monoclonal antibody (CD_(41)) APAAP immunoenzymatic method to observe the megakaryocytes in bone marrow and part of the peripheral blood of 40 patients with leukemia. The result is as follows: