在欧洲和北美,睾丸癌发病率增加超过了多数其他癌,有人提出这种趋势是由于饮食习惯、合成雌激素和环境雌激素化学物质的变化引起子宫内接触雌激素增多造成的,其中一种假说认为人体内主要的滴滴涕(DDT)代谢物,即 P,P’-DDE(二氯二苯-二氯乙烯)导致男性发育异常,因为P,P’-DDE是一种强有力的雄性激素拮抗剂。已发现接触此类化合物的胎儿和新生儿睾丸癌发生率增加。虽然20年前就明令禁止和严格限制使 In Europe and North America, the incidence of testicular cancer has increased more than most other cancers. It has been suggested that this trend is caused by increased estrogen exposure in the uterus due to changes in dietary habits, synthetic estrogens, and environmental estrogen chemicals. The hypothesis is that the main DDT metabolite in the human body, namely P,P’-DDE (dichlorodiphenyl-dichloroethylene), causes male dysplasia because P,P’-DDE is a potent male hormone. Antagonists. Fetal and neonatal testicular cancer incidence has been found to increase with exposure to such compounds. Although it was banned and strictly restricted 20 years ago,