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[目的]探讨缬沙坦与氨氯地平联合用药对原发性高血压的疗效,以积累经验,指导临床工作。[方法]选取某院门诊治疗的240例原发性高血压患者,随机分为二组,观察组共120例,选用缬沙坦与氨氯地平联合治疗;对照组共120例,单纯应用缬沙坦治疗。比较二种治疗方法的疗效。[结果]治疗后第4周末、第8周末随访,观察组血压明显下降,疗效均明显优于对照组;观察组第8周末血压明显下降,疗效明显明显优于第4周末,观察组与对照组的副作用均较轻微。[结论]原发性高血压患者应用缬沙坦与氨氯地平联合治疗,效果明显,副作用少,可以在临床中应用。
[Objective] To investigate the curative effect of valsartan combined with amlodipine on essential hypertension in order to accumulate experience and guide clinical work. [Methods] A total of 240 patients with essential hypertension treated in a hospital were randomly divided into two groups. The observation group consisted of 120 patients. Valsartan and amlodipine were used in combination. In the control group, 120 patients were treated with Vale alone Sartan treatment. Compare the efficacy of the two treatment methods. [Results] At the end of the 4th and 8th week after treatment, the blood pressure of the observation group decreased significantly, and the curative effect was obviously better than that of the control group. At the end of the 8th week, the blood pressure of the observation group decreased obviously, and the curative effect was obviously better than the 4th weekend. Side effects were mild. [Conclusion] The combination of valsartan and amlodipine in patients with essential hypertension has obvious effect and few side effects and can be used clinically.