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目的观察洪霞主任医师自拟方清热凉血汤治疗儿童单纯性血尿的临床治疗效果。方法将60例患儿随机分为中药组和对照组各30例。中药组给予自拟方剂清热凉血汤,水煎300mL,日一剂,早晚分服。疗程3个月。对照组给予西医对症治疗,潘生丁12.5~25 mg,3次/日,口服;复方芦丁片1片,3次/日,口服;维生素E50mg,1次/日,口服。疗程3个月。结果中药组与对照组在治疗前、治疗1月、治疗2月、治疗3月后尿沉淀红细胞数比较,治疗前尿沉淀红细胞数比较t=0.27相比无差异性(P>0.05),治疗1月后尿沉淀红细胞数比较t=1.52相比无差异性(P>0.05),治疗2月尿沉淀红细胞数比较t=2.11相比有差异性(P<0.05),治疗3月后尿沉淀红细胞数比较t=3.15相比有显著差异性(P<0.01)。两组治疗效果比较,具有显著差异,x~2=8.17,P<0.05,说明中药组治疗3个月后治疗效果优于对照组。随访半年,中药组复发3例,复发率11.53%,对照组复发6例,复发率35.29%,两组复发率相比较有显著差异,(P<0.05),说明中药组长期效果优于对照组。结论清热凉血法对儿童单纯性血尿治疗效果明显,值得推广。
Objective To observe the clinical therapeutic effect of Hong Xia, a chief physician who has authored Fang Qingre Liangxue Decoction in treating children with simple hematuria. Methods Sixty children were randomly divided into TCM group and control group, 30 cases each. Chinese medicine group given self-prescription Prescription Qingre Liangxue Decoction, decoction 300mL, a day, morning and evening service. Course of 3 months. The control group was given western medicine symptomatic treatment, dipyridamole 12.5 ~ 25 mg, 3 times / day, oral; compound rutin tablets 1, 3 times / day, oral; vitamin E50mg, 1 times / day, orally. Course of 3 months. Results Before treatment, the number of erythrocytes in urine of the Chinese medicine group and the control group before treatment, 1 month after treatment, 2 months after treatment and 3 months after treatment were significantly higher than those before treatment (t = 0.27) (P> 0.05) After 1 month, the number of urinary sedimentation erythrocytes was no difference (t> 1.52) (P> 0.05), the number of urine sedimentation erythrocytes in February was significantly different from that of t = 2.11 (P <0.05) Red blood cell count was significantly higher than t = 3.15 (P <0.01). There was significant difference between the two groups in the treatment effect, x ~ 2 = 8.17, P <0.05, indicating that the treatment effect of the traditional Chinese medicine group after 3 months was better than that of the control group. The follow-up of six months, the traditional Chinese medicine group of 3 cases of recurrence, the recurrence rate was 11.53%, 6 cases of recurrence in the control group, the recurrence rate was 35.29%, the recurrence rate of the two groups were significantly different (P <0.05) . Conclusion The method of clearing away heat and cooling blood is effective in treatment of children with simple hematuria and is worth promoting.