胰腺炎、糖尿病酮症酸中毒和肝硬变时肾脏淀粉酶廓清增加的机制尚不清楚,但临床上常有高胰升糖素血症。胰升糖素能增加肾小球的滤过率,因此设想,这种胰激素可能对肾脏排泄淀粉酶的增加起主要作用。Marten等证明,一次药理学剂量的胰升糖素能使淀粉酶的廓清增加。本文旨在研究生理的血浆胰升糖素浓度对肾脏廓清淀粉酶的影响。 Pancreatitis, diabetic ketoacidosis and cirrhosis of renal amylase clearance mechanism is not clear, but clinically high hyperglycemia. Glucagon increases the glomerular filtration rate, so it is assumed that this pancreatic hormone may play a major role in the increase of renal excretion of amylase. Marten et al. Demonstrated that a pharmacological dose of glucagon increased the amylase clearance. The purpose of this article is to study the effects of physiological plasma glucagon concentration on amyloplast urease in the kidneys.