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目的:探讨200例早产儿肺透明膜病(HMD)的临床治疗的疗效。方法:采用回顾性分析的方法,分析本院儿科收治的200例HMD患儿,依据治疗方法的不同将患儿随机分为氨溴索与高频振荡通气联合应用治疗组(观察组)100例,肺表面活性物质(PS)治疗组(对照组)100例。结果:观察组与对照组在治疗后血气分析结果、并发症及存活率等方面无显著性差异(P>0.05);观察组的治疗时间明显长于对照组(P<0.05),但是观察组的住院费用明显低于对照组(P<0.05)。结论:两种治疗方法对治疗早产儿肺透明膜病均有明显疗效,临床可依据患者实际情况选用。
Objective: To investigate the clinical effect of 200 cases of premature infants with hyaline membrane disease (HMD). Methods: A retrospective analysis of 200 cases of children admitted to our hospital pediatric HMD, according to the different treatment of children were randomly divided into ambroxol and high frequency oscillation ventilation combined with the treatment group (observation group) 100 cases , 100 cases of pulmonary surfactant (PS) treatment group (control group). Results: There was no significant difference between the observation group and the control group in the blood gas analysis results, complications and survival rate after treatment (P> 0.05). The treatment time in the observation group was significantly longer than that in the control group (P <0.05) Hospitalization costs were significantly lower than the control group (P <0.05). Conclusion: The two treatment methods for the treatment of hyaline membrane disease in preterm children have a significant effect, the clinical can be selected according to the actual situation of patients.