[目的]研究一种合成3-二正丙胺基丙烯醛过程中代替剧毒物质丙炔醇的方法。[方法]用活性二氧化锰作为催化剂,空气作为氧化剂,3-氯丙烯醇与二正丙胺反应合成目标产物。[结果]3-二正丙胺基丙烯醛收率达90.1%。[结论]用3-氯丙烯醇制备3-二正丙胺基丙烯醛可以得到较高的收率,并避免使用剧毒原料丙炔醇,具有工业化应用前景。 [Objective] The research aimed to study a new method of synthesizing 3-di-n-propylaldehyde instead of the highly toxic propargyl alcohol. [Method] Active manganese dioxide was used as catalyst and air was used as oxidant. 3-Chloropropenol was reacted with di-n-propylamine to synthesize the target product. [Result] The yield of 3-di-n-propylacrolein reached 90.1%. [Conclusion] The preparation of 3-di-n-propylalcylaldehyde with 3-chloropropenol could get higher yield and avoid the use of virulent propargyl alcohol, which has the industrial application prospect.