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最近在美国出售了一种新的治疗多种感染的非肠道使用的半合成头孢菌素,羟苄磺唑头孢菌素钠(Cefonicid Sodium).该抗生素的结构与“第二代”头孢菌素——甲酰苄唑头孢菌素相类似.抗菌活性该药体外活性与甲酰苄唑头孢菌素相类似.但是它对革蓝氏阳性球菌(包括金黄色葡萄球菌、酿脓链球菌和肺炎球菌)的活性比甲酰苄唑头孢菌素或者呋肟头孢菌素都低.羟苄磺唑头孢菌素对淋球菌(包括产生青霉素酶的菌株)的活性略比甲酰苄唑
Recently sold a new parenteral semi-synthetic cephalosporin, Cefonicid Sodium, for the treatment of multiple infections in the United States. The antibiotic has the same structure as the “second generation” Cephalosporin - formylbenzothiazide cephalosporin similar antibacterial activity of the drug in vitro activity and formylzole cephalosporins similar, but it is Gram-positive cocci (including Staphylococcus aureus, pygery chain Cocci and pneumococci) are less active than the ceftriaxone cefotaxime or fufosyclo cephalosporin cefotaximes. The activity of cefotaximes against Neisseria gonorrhoeae (including those producing penicillinase)