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目的通过对2004-2009年山西省浑源县布鲁氏菌病(布病)发病情况的总结,分析布病在本地区的流行状况和趋势,为本地区布病防控提供参考意见。方法选取2004-2009年本地区布病疫情资料,对发病地、性别、年龄、职业等指标进行分析。对2008-2009年79份布病门诊患者血清进行虎红平板凝集试验(RBPT)和试管凝集试验(SAT)检测分析,并对11份正在发热患者血液进行细菌培养分离。结果 2004-2009年发病人数分别为58、99、158、232、188和171例,总数为906例。30~60岁患者共639例,占69.76%。其中以50~60岁最多,共286例,占31.22%。男性733例,占80.02%,女性173例,占19.09%。农民805例,占87.89%。永安和沙圪坨两地发病人数分别为143和112例,明显多于其他乡镇。餐饮工作者和学生人数分别从0例和1例增长至7例和8例。79份血清中57份RBPT和SAT均为阳性,59份RBPT阳性,58份SAT阳性。11份血培养分离到2株布鲁氏菌,经中国疾病预防控制中心传染病所鉴定全部为羊种Ⅲ型。结论 2004-2009年,本地区布病发病人数总体上呈增长趋势。全县18个乡镇均有新发病例,个别乡镇各年发病人数均明显高于其他乡镇。各年龄段均有发病,以中年为主,50~60岁最多,男性多于女性。农民占绝大多数,学生和餐饮工作者发病呈增长趋势。菌种以羊种Ⅲ型为主。
Objective To summarize the incidence of Brucellosis (Brucellosis) in Hunyuan County of Shanxi Province from 2004 to 2009, and to analyze the prevalence and trend of brucellosis in this area and provide reference for the prevention and control of brucellosis in this area. Methods The epidemic situation of brucellosis in this area was selected from 2004 to 2009 to analyze the incidence, sex, age, occupation and other indicators. Eighty-seven brucellosis outpatients were tested for RBPT and SAT in 2008-2009. Blood samples were collected from 11 febrile patients for bacterial culture. Results The number of cases from 2004 to 2009 were 58, 99, 158, 232, 188 and 171 respectively, with a total of 906 cases. A total of 639 patients aged 30 to 60 years, accounting for 69.76%. Among them, 50 to 60 years old the most, a total of 286 cases, accounting for 31.22%. There were 733 males, accounting for 80.02% and 173 females, accounting for 19.09%. 805 farmers, accounting for 87.89%. There were 143 and 112 cases in Yong’an and Shahuo Tuo, respectively, which were significantly more than those in other townships. The number of catering workers and students increased from 0 cases and 1 case to 7 cases and 8 cases, respectively. Of the 79 sera, 57 were positive for RBPT and SAT, 59 were RBPT positive and 58 were SAT. Two strains of Brucella were isolated from 11 blood cultures, all of which were identified as Type III by the Institute of Infectious Diseases, Chinese Center for Disease Control and Prevention. Conclusion From 2004 to 2009, the incidence of brucellosis in this area showed a general trend of increase. 18 new towns in the county have new cases, the incidence of individual towns in each year were significantly higher than other towns. The incidence of all age groups, mainly middle-aged, 50 to 60 years of age, more men than women. The vast majority of peasants, students and catering workers showed an increasing trend of incidence. Species to sheep type Ⅲ based.