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采用酶联免疫吸附法（ＥＬＩＳＡ），对４１例原发性肺癌及１７例良性肺病，进行神经元烯醇化酶（ＮＳＥ）及血清脂质结合唾液酸（ＬＳＡ）测定，探讨其对肺癌的诊断价值。结果显示，肺癌组ＮＳＥ和ＬＳＡ水平均明显高于良性肺病组（Ｐ＜０．０１）；ＮＳＥ在非小细胞肺癌中阳性率为７３．７％，特异性９０．０％，故也是非小细胞癌的重要标记物。对比肺癌患者治疗前后检测水平，表明ＮＳＥ和ＬＳＡ变化与治疗效果、癌转移等因素有关，因此可作为肺癌的监测指标。
ELISA was used to determine the neuronal enolase (NSE) and serum lipid-associated sialic acid (LSA) in 41 cases of primary lung cancer and 17 cases of benign lung disease. The diagnosis of lung cancer was explored. value. The results showed that the levels of NSE and LSA in lung cancer group were significantly higher than those in benign lung disease group (P<0.01). The positive rate of NSE in non-small cell lung cancer was 73.7%, and the specificity was 90.0%. An important marker of cell cancer. Comparison of the level of detection before and after treatment in patients with lung cancer, indicating that NSE and LSA changes and treatment effects, cancer metastasis and other factors, it can be used as a monitoring indicator of lung cancer.