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造血基质是干细胞增殖和分化的场所,研究其放射敏感性是很有意义的。骨髓和脾脏的造血基质放射耐受性较高,2000rad 的照射仍能维持造血细胞均生长,3000 rad 以上剂量的损伤才不能修复。但基质的间充质细胞及其衍化的各种细胞,当切除其骨髓细胞而引起增殖时,可能会提高其放射敏感性。机械损伤大鼠和家兔的骨髓,照射剂量须超过1000 rad 时,才能影响其修复过程。切除骨髓后,其再生障碍的平均
The hematopoietic matrix is a site for the proliferation and differentiation of stem cells and it makes sense to study its radiosensitivity. The hematopoietic matrix of bone marrow and spleen is highly radio-tolerant. Radiation at 2000 rad can still maintain hematopoietic cell growth, and the damage above 3000 rad can not be repaired. However, the stromal mesenchymal cells and the various cells they derive may increase their radiosensitivity when their bone marrow cells are excised to cause proliferation. Mechanical injury rat and rabbit bone marrow, irradiation dose should be more than 1000 rad, can affect the repair process. After resection of the bone marrow, the average of its aplastic failure