作者前瞻性地研究了某大学综合医院在1979和1982两年中,经临床和细菌学诊断的446例败血症患者的病因、流行病学、临床及其预后。败血症发生率占住院人数的8.4‰,其中内科病员为59‰,外科病员为13‰。47.1%患者为院外发生感染,52.9%系院内感染。男性发病数略多于女性,分别为53.8%和46.2%,60岁以上患者占53.1%。多数患者(71.3%)有基础病或危险因素存在。常见的临床表现为发热、心动过 The authors prospectively studied the etiology, epidemiology, clinical, and prognosis of 446 sepsis patients clinically and bacteriologically diagnosed in a university general hospital in 1979 and 1982. The incidence of sepsis accounted for 8.4 ‰ of hospitalizations, including 59 ‰ for medical patients and 13 ‰ for surgical patients. 47.1% patients were hospitalized outside the hospital, 52.9% were nosocomial infections. The incidence of males was slightly more than that of females, accounting for 53.8% and 46.2% respectively, with 53.1% of those over 60 years old. The majority of patients (71.3%) had underlying diseases or risk factors. Common clinical manifestations of fever, heartbeat