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目的:检测急性一氧化碳中毒(ACOP)患者心肌肌钙蛋白Ⅰ(TnI)的变化及临床意义。方法:检测716例急性一氧化碳中毒患者的心肌肌钙蛋白Ⅰ的化验结果,分析造成心肌损害可能性的比率及严重程度。结果:只有重度中毒患者及既往有明确冠心病的中度中毒患者的肌钙蛋白明显升高占急性一氧化碳中毒患者的不足13%。结论:只有重度急性一氧化碳中毒和既往有冠心病史患者出现心肌损害的可能性大。
Objective: To detect the changes of cardiac troponin Ⅰ (TnI) in patients with acute carbon monoxide poisoning (ACOP) and its clinical significance. Methods: The cardiac troponin I assay was performed in 716 patients with acute carbon monoxide poisoning and the rate and severity of myocardial damage were analyzed. RESULTS: Only patients with severe poisoning and those with moderately documented coronary heart disease had significantly higher troponin values than 13% of patients with acute carbon monoxide poisoning. CONCLUSIONS: Only patients with severe acute carbon monoxide poisoning and previous history of coronary heart disease have a high likelihood of developing myocardial damage.