目的探讨血浆D-二聚体(D-Dimer)水平与结直肠癌转移的关系。方法采用病例对照的方法回顾性分析我院235例结直肠癌患者中,血浆D-二聚体水平与结直肠癌转移的关系。结果检测结直肠癌患者中血浆D-二聚体阳性组(>250μg/L)132例,发生淋巴结及远处转移81例;阴性组(≤250μg/L)103例,发生淋巴结及远处转移42例,两组比较差异有统计学意义(P<0.05)。结论血浆D-二聚体与结直肠癌的病情发展有相关性。 Objective To investigate the relationship between plasma D-dimer and metastasis of colorectal cancer. Methods The case-control method was used to retrospectively analyze the relationship between plasma D-dimer level and colorectal cancer metastasis in 235 patients with colorectal cancer in our hospital. Results There were 132 cases with positive plasma D-dimer (> 250μg / L) in colorectal cancer, 81 cases with lymph node metastasis and distant metastasis, and 103 cases with negative (≤250μg / L) lymph node and distant metastasis 42 cases, the difference between the two groups was statistically significant (P <0.05). Conclusion Plasma D-dimer is associated with the progression of colorectal cancer.