枸橼酸哌哔嗪为目前较理想的驱蛔药物之一。该药有疗效高、毒性低、用法简便等优点,为广大医务人员所常用。但在使用过程中,发现枸橼酸哌哔嗪亦有一定的毒性反应,我们在半年内观察了以该药驱蛔的患儿100例,现就其毒性反应分析报告如下:驱虫方法:以驱蛔灵糖浆或片剂驱虫,剂量为160毫克/公斤体重,连服两晚,1次剂量不超过3.2克。对入院时患有其他疾病者,一律于临床痊愈或显著好转后驱虫。毒性反应:100例中有14例出现轻重不一的反应,反应率为14％,未见有年龄或性别 Pipeipiperazine citrate is currently one of the ideal antidiabetic drugs. The drug has high efficacy, low toxicity, ease of use and other advantages, for the majority of medical staff commonly used. However, in the course of using it, we found that pipeiperazine citrate also has some toxic reaction. We observed 100 cases of children who were treated with this drug within six months. Now we report the following toxicity analysis: Deworming method: To drive Guajiao syrup or tablet deworming, a dose of 160 mg / kg body weight, and even served two nights, a dose of not more than 3.2 grams. On admission to patients suffering from other diseases, all clinically cured or significantly improved after deworming. Toxicity reactions: 14 of 100 cases appeared in different severity, response rate was 14%, no age or gender