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目的评价舌下含服米索前列醇配伍异丙酚用于人工流产镇痛及对宫颈的松弛效果。方法将要求无痛人工流产的早孕健康妇女分为两组。A组术前30min舌下含服米索前列醇0.2mg,然后在异丙酚静脉麻醉下行人工流产术;B组直接在异丙酚静脉麻醉下行人工流产术,对两组进行多项指标对比分析。结果两组手术麻醉效果差异无统计学意义(P>0.05)。但A组宫颈松弛明显好于B组,手术时间也较B组明显缩短,且手术易于操作,术中出血量、术后阴道流血时间均明显少于或短于B组。两组均无人工流产综合征发生,但A组和B组分别有2例和3例发生呼吸抑制。结论异丙酚静脉麻醉下实施人工流产术前30min舌下含服米索前列醇0.2mg,有较好的宫颈松弛作用,可增强子宫收缩,手术易于操作,术中出血少,术后阴道流血时间短,值得临床应用。
Objective To evaluate the sublingual misoprostol compatibility propofol for induced abortion and cervical relaxation. Methods Early pregnancy healthy women who asked for painless abortion were divided into two groups. A group 30min preoperative sublingual misoprostol 0.2mg, and then in the propofol anesthesia underwent artificial abortion; B group directly under the anesthesia of propofol artificial abortion, the two groups were compared to a number of indicators analysis. Results There was no significant difference in anesthesia between the two groups (P> 0.05). However, cervical relaxation in group A was significantly better than that in group B, the operation time was significantly shorter than that in group B, and the operation was easy to operate. The amount of bleeding during operation and postoperative vaginal bleeding time were significantly shorter or shorter than those in group B. No abortion syndrome occurred in either group, but respiratory depression occurred in 2 and 3 patients in group A and group B, respectively. Conclusions Intravenous administration of misoprostol 0.2 mg 30 minutes before artificial abortion under propofol intravenous anesthesia has good cervix relaxation effect, which can enhance uterine contractions, easy operation of the operation, less intraoperative bleeding, postoperative vaginal bleeding Short time, it is worth clinical application.