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作为一种神经递质,多巴胺(DA)在中枢神经系统中的作用已被认识多年。多巴胺能神经在各种结构中得以证实,包括神经节、延髓、丘脑下部。这些部位的多巴胺能神经能防止巴金森神经机能障碍(Parkisonism)症状;产生恶心、呕吐;抑制催乳素分泌。近年来,越来越多的证据证明DA作为一种神经递质,在外周神经系统也存在。一定量的DA在交感神经节、交感神经以及人体某些组织中被发现。特异性DA受体激活后,可增加肾、肠系膜、冠状动脉及脑血管的血流,促进肾排钠,抑制脑垂体分泌催
As a neurotransmitter, the role of dopamine (DA) in the central nervous system has been known for many years. Dopaminergic nerves were confirmed in various structures, including ganglia, medulla oblongata, and hypothalamus. Dopaminergic neurons in these areas prevent Parkinsonism symptoms; nausea, vomiting; and inhibition of prolactin secretion. In recent years, more and more evidence that DA as a neurotransmitter in the peripheral nervous system also exists. A certain amount of DA is found in sympathetic ganglia, sympathetic nerves and certain tissues in the body. Specific DA receptor activation, can increase renal, mesenteric, coronary and cerebrovascular blood flow, promote renal row of sodium, inhibit pituitary secretion