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由7个欧洲中心参加此项回顾性研究,旨在了解预激综合征(WPW)病人发生心室颤动(VF)的危险因素。方法:共收集到WPW发生VF的病人26例,其中3例因发现有冠心病而剔除。由第一作者亲自到每个中心进行调查,并与各中心的主要研究者共同分析资料。在23例中有22例的电生理研究资料可采用,并与无自发VF的连续100例WPW相比较。结果:在VF组23例中有9例在第一次VF发作以前曾接受抗心律失常治疗。9例中只有1例是在抗心律失常药(维拉帕米)治疗时发生VF的。紧接VF发作前被证实有室上性快速心律失常的共14例,占VF组的61％。其中心房颤动(房颤)9例,占39％;心房扑动(房扑)2例(经旁道1∶1顺传);顺向型和逆向型房室折返性心动过
Seven European centers participated in this retrospective study to understand the risk factors for ventricular fibrillation (VF) in patients with WPW. Methods: A total of 26 cases of VF with WPW were collected, of which 3 cases were excluded because of coronary heart disease. The first author conducted a survey of each center in person and analyzed the data with key researchers at each center. Electrophysiological data were available for 22 of 22 patients and compared with 100 consecutive WPWs without spontaneous VF. Results: Nine of the 23 patients in the VF group received anti-arrhythmic treatment prior to the first VF episode. Only one of nine patients developed VF during antiarrhythmic (verapamil) treatment. A total of 14 cases of supraventricular tachyarrhythmias were confirmed immediately before VF onset, accounting for 61% of the VF group. Among them, 9 cases were atrial fibrillation (atrial fibrillation), accounting for 39%; 2 cases of atrial flutter (atrial flutter) (1: 1 bypass); forward and reverse atrioventricular reentrant tachycardia