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目的探讨多层螺旋CT(MSCT)灌注成像对外周型小结节状肺腺癌淋巴结转移的诊断价值。方法选取2012年1月至2014年6月间河北省沧州市人民医院收治的260例肺腺癌患者的MSCT影像特征与灌注参数进行回顾性分析,采用多元相关分析探讨影像特征、灌注参数与病理特征的关系。结果不同分化程度患者的血流量(BF)、血容量(BV)和强化峰值(PEI)比较差异有统计学意义(P<0.05),且BF和PEI随着分化程度降低而降低,差异有统计学意义(P<0.05)。淋巴结转移患者的BF、BV和PEI比无淋巴转移患者均低,术后出现转移或复发患者的BF和PEI比术后无转移或复发的患者低,差异均有统计学意义(均P<0.05)。结论 MSCT灌注成像能够预测淋巴结转移与术后复发的可能性,对临床诊断外周型小结节状肺腺癌淋巴结转移具有重要意义。
Objective To investigate the diagnostic value of multislice spiral CT (MSCT) perfusion imaging in lymph node metastasis of peripheral small nodular lung adenocarcinoma. Methods From January 2012 to June 2014, 260 patients with lung adenocarcinoma admitted to Cangzhou People’s Hospital of Hebei Province were retrospectively analyzed for MSCT imaging features and perfusion parameters. Multivariate correlation analysis was used to explore the imaging features, perfusion parameters and pathology Characteristics of the relationship. Results The blood flow (BF), blood volume (BV) and enhancement peak (PEI) in patients with different degrees of differentiation were significantly different (P <0.05), and BF and PEI decreased with the degree of differentiation decreased Significance (P <0.05). BF, BV and PEI in patients with lymph node metastasis were lower than those without lymph node metastasis, BF and PEI in patients with metastasis or recurrence were lower than those without metastasis or recurrence (all P <0.05 ). Conclusion MSCT perfusion imaging can predict the possibility of lymph node metastasis and postoperative recurrence, and is of great significance for clinical diagnosis of lymph node metastasis of peripheral small nodular lung adenocarcinoma.