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患者,男性,66岁。肺心病,处于哮喘持续状态,缓慢静脉注射氨茶碱0.25g加25%葡萄糖溶液20ml,注射至约10分钟时突然出现哮喘加重、神志不清、四肢抽动,昏迷、呼吸心跳停止而死亡。患者,女性,52岁。肺心病,因气喘较重缓慢静注氨茶碱0.25g加25%葡萄糖溶液20ml,注射约15分钟。注射完毕即出现头昏、心悸、呼吸困难、神志不清、心跳停止而死亡。氨茶碱静注过速、浓度过高时,可致心肌过度兴奋而发生心悸、惊厥、血压剧降等,儿童尤应慎用。本文2例均为常规剂量缓慢静注而引起死亡,
Patient, male, 66 years old. Pulmonary heart disease, in a state of asthma, slowly intravenous aminophylline 0.25g plus 25% glucose solution 20ml, injection of about 10 minutes suddenly increased asthma, unconsciousness, limbs twitch, coma, death from respiratory arrest. Patient, female, 52 years old. Pulmonary heart disease, due to severe asthma intravenous aminophylline 0.25g plus 25% glucose solution 20ml, injection of about 15 minutes. Immediately after injection, dizziness, palpitations, dyspnea, unconsciousness, cardiac arrest and death. Aminophylline intravenous overdose, the concentration is too high, can cause over-excitement and heart palpitations, convulsions, sudden drop in blood pressure, etc., children should be used with caution. Two cases of this paper are slow intravenous infusion of conventional dose and cause death,