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应用流式细胞技术检测了共40例正常孕妇分娩前后和新生儿脐血的白细胞和淋巴细胞亚群。其中阴道分娩组20例,选择性剖宫产组20例。结果:分娩前后母体白细胞总数和中性粒细胞、NK细胞活性以及CD8、CD19亚群均相差不显著,而产后母血CD4亚群升高,CD3、CD4/CD8亦升高;剖宫产或阴道分娩者母体和新生儿淋巴细胞亚群相差不显著,但阴道分娩新生儿的白细胞总数、中性粒细胞比例、单核细胞和NK细胞显著升高。提示:产后母体免疫状况由孕期的抑制转入增强,分娩方式对母体免疫状况无明显影响,但阴道分娩使新生儿的非特异性免疫功能增强,对新生儿有益。
Flow cytometry was used to detect a total of 40 normal pregnant women before and after delivery and neonatal cord blood leukocytes and lymphocyte subsets. Including 20 cases of vaginal delivery group, selective cesarean section in 20 cases. Results: Before and after delivery, the total number of maternal white blood cells and neutrophils, NK cell activity and CD8, CD19 subpopulations were not significantly different, while postpartum maternal blood CD4 subpopulation, CD3, CD4 / CD8 also increased; cesarean section or The vaginal delivery of maternal and neonatal lymphocyte subsets difference was not significant, but the vaginal delivery of neonatal white blood cells, neutrophil ratio, monocytes and NK cells was significantly increased. Tip: postpartum maternal immune status turned from suppression during pregnancy increased, mode of delivery of maternal immune status had no significant effect, but the vaginal delivery of neonatal non-specific immune function increased, beneficial to the newborn.