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目的:探讨腹腔镜手术治疗急性结石性胆囊炎对炎性因子水平与胃肠功能的影响。方法:选择河南大学第一附属医院2014年8月至2016年3月收治的84例急性结石性胆囊炎患者为研究对象,以随机数字表法分为2组,观察组42例接受腹腔镜手术治疗,对照组42例采取常规开腹手术治疗,对两组患者术后炎性因子及胃肠功能恢复情况进行观察。结果:观察组肛门排气时间、肠鸣音恢复时间、肛门排便时间明显较对照组短,两组差异有统计学意义(P<0.05);术前两组患者超敏C反应蛋白(hs-CRP)、肿瘤坏死因子α(TNF-α)、白细胞介素-6(IL-6)等炎性因子水平比较,差异均无统计学意义(P>0.05),观察组术后48 h的炎性因子水平显著低于对照组,差异有统计学意义(P<0.05)。结论:腹腔镜手术治疗急性结石性胆囊炎可缩短术后胃肠功能恢复时间。
Objective: To investigate the effect of laparoscopic surgery on acute calcific cholecystitis on the level of inflammatory factors and gastrointestinal function. Methods: A total of 84 patients with acute calculous cholecystitis admitted to the First Affiliated Hospital of Henan University from August 2014 to March 2016 were selected and divided into two groups according to the random number table. The observation group received 42 cases of laparoscopic surgery In the control group, 42 patients underwent conventional laparotomy, and postoperative inflammatory factors and gastrointestinal function recovery were observed in both groups. Results: The anal exhaust time, bowel sound recovery time and anal defecation time in the observation group were significantly shorter than those in the control group (P <0.05). The hs- CRP, TNF-α, IL-6, etc. There was no significant difference between the two groups (P> 0.05). The levels of inflammatory cytokines The level of sex factor was significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion: Laparoscopic surgery for acute calculous cholecystitis can shorten the postoperative recovery time of gastrointestinal function.