该前瞻性研究旨在检测单用唑尼沙胺（zonisamide，ZNS）治疗新诊断的婴儿痉挛症（IS）的近期疗效，方法1995年1月～1996年1月间日本11个医院的13例新诊断的IS患儿，均有典型的临床痉挛发作，突发性智力减退和脑电图（EEG）高幅节律失常或变异性高幅节律失常．2例对大剂量VtB6治 This prospective study aimed to examine the short-term efficacy of zonisamide (ZNS) alone in the treatment of newly diagnosed infantile spasms (IS). Methods From January 1995 to January 1996, 13 patients from 11 hospitals in Japan Newly diagnosed IS children have typical clinical spasms of seizures, sudden dementia, and high-amplitude rhythm disorders or high-amplitude arrhythmias of EEG. 2 cases of high-dose VtB6 treatment