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原发性食管小细胞癌(PESCC)是一种十分少见的食管高度恶性肿瘤。自1952年MCKeown首例报告以来,国内陆续报告。近年来由于对本症认识水平的提高,临床报告有增多的趋势。我们自1988年2月～1996年3月共收治8例。现报告如下: 1 临床资料 1.1 性别与年龄 本组男性6例,女性2例;年龄40岁～74岁,平均61岁。 1.2 临床表现 均以进行性吞咽困难为主要症状,伴胸骨后疼痛或不适3例,进行性消瘦4例,就诊时有颈部淋巴结肿大1例。症状持续时间为3周～5个月。 1.3 特殊检查 本组8例均经食管钡透检查诊断为食管癌,其中6例行食管内窥镜活检确诊;行胸部CT检查者5例,4例提示纵隔淋巴结肿大;术前均摄x线胸片及经腹部B超检查均未发现转移灶。
Primary small cell carcinoma of the esophagus (PESCC) is a very rare high grade malignant tumor of the esophagus. Since the first case report of MCKeown in 1952, reports have been continuously reported in China. In recent years, due to the increase in the level of awareness of the disease, clinical reports have increased. We have treated 8 cases from February 1988 to March 1996. The report is as follows: 1 Clinical data 1.1 Sex and age There are 6 males and 2 females in this group, aged 40 to 74 years with an average age of 61 years. 1.2 Clinical manifestations All of them had main symptoms of progressive dysphagia, 3 cases with poststernal pain or discomfort, 4 cases of progressive emaciation, and 1 case of cervical lymphadenopathy. Symptoms last for 3 weeks to 5 months. 1.3 special examination of this group of 8 cases were diagnosed as esophageal cancer by esophageal fistula examination, including 6 cases of esophageal endoscopic biopsy confirmed; chest CT examination in 5 cases, 4 cases of mediastinal lymph nodes; preoperative average photo x There were no metastatic lesions detected by chest X-ray and transabdominal ultrasonography.