以2,3-二氯吡嗪及取代苯硼酸为起始原料,经Suzuki偶联反应构筑分子骨架,合成了不同取代基修饰的新型2,3-二芳基取代吡嗪衍生物;目标化合物结构经1H NMR,IR和EI-MS分析表征;探讨了底物用量比及不同结构芳硼酸对反应的影响.结果表明,在无氧条件下,碱性二氧六环中,使用Pd(PPh_3)_4催化剂,除邻氰基苯硼酸外,所有反应均可有效进行,目标产物收率可达44%~93%. With 2,3-dichloropyrazine and substituted phenylboronic acid as starting materials, the molecular skeleton was constructed by Suzuki coupling reaction to synthesize novel 2,3-diaryl substituted pyrazine derivatives with different substituents. The target compounds The structures of the compounds were characterized by 1H NMR, IR and EI-MS. The effects of the ratio of substrate to arylboronic acid on the reaction were discussed. The results showed that Pd (PPh_3 ) _4 catalyst, in addition to o-cyanophenylboronic acid, all reactions can be effectively carried out, the target product yield up to 44% to 93%.