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针对病因和发病机理的治疗理论,得到了进一步的发展和印证1972年,Cameron 根据肾炎的病因和免疫发病机理,提出了针对病因和发病机理治疗肾炎的理论。十余年来,这一理论已得到了许多临床和实验研究的支持,因而1984年 Cameron 在第九届国际肾脏病会议上,重申并发展了他的免疫治疗理论,概括如下:一.清除引起肾炎的抗原(一)从环境中清除引起肾炎的抗原:采用公共卫生方法。(二)清除肾炎病人体内的致肾炎抗原:如切除肿瘤,控制感染,清除病灶等。(三)从肾炎病人血浆中清除抗原:采用血浆置换疗法。二.针对引起肾脏免疫损伤的各个环节(一)抑制或移除抗体:可用血浆置换术、免疫抑制剂及给予抗特殊型抗体等方法。(二)改善抗体反应:可用免疫调节药物,抗特殊型抗
Therapeutic theory of etiology and pathogenesis has been further developed and confirmed In 1972, Cameron according to the etiology of nephritis and immune pathogenesis, put forward the theory of etiology and pathogenesis of nephritis treatment. This theory has been supported by many clinical and experimental studies for more than ten years. Therefore, in 1984, Cameron reiterated and developed his immunotherapy theory at the Ninth International Nephrology Conference, summarized as follows: Nephritis antigen (A) from the environment to clear the anti-nephritis antigen: The use of public health methods. (B) clear nephritis in patients with anti-nephritic antigen: such as tumor removal, infection control, removal of lesions. (C) remove antigen from the plasma of patients with nephritis: the use of plasma exchange therapy. Two. Aim at causing all aspects of renal immune injury (A) inhibition or removal of antibodies: Available plasma exchange, immunosuppressive agents and anti-specific antibodies and other methods. (B) to improve antibody response: Available immunomodulatory drugs, anti-special anti-type