论文部分内容阅读
1991年10月至1997年6月通过遗传咨询观察了智力低下(MR)儿童1680例,其中男性占53.3%,女性占46.7%;伴癫痫者占11.2%,伴脑瘫者占21%;第一胎占82.6%;轻度MR占73.8%,中度MR占22.9%,重度MR占3.3%。染色体核型异常检出率为14.6%,其中常染色体异常占73.1%,性染色体异常占26.9%。在病因探讨中,属于出生前因素占41.2%,出生时因素占26.5%,出生后因素占2.7%,原因不明占29.6%。
From October 1991 to June 1997, 1680 children with mental retardation (MR) were observed through genetic counseling, of which 53.3% were male and 46.7% were female; those with epilepsy accounted for 11.2%, with cerebral palsy Accounting for 21%; first birth accounted for 82.6%; mild MR accounted for 73.8%, moderate MR accounted for 22.9%, severe MR accounted for 3.3%. Chromosome karyotype abnormality detection rate was 14.6%, of which autosomal abnormalities accounted for 73.1%, sex chromosome abnormalities accounted for 26.9%. In the etiology of the study, 41.2% of prenatal factors, 26.5% of postnatal factors, 2.7% of postnatal factors and 29.6% of unknown reasons.