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目的:观察老年高血压患者血清尿酸和高敏C反应蛋白水平与颈动脉内-中膜厚度的相关性。方法:测定164例老年原发性高血压患者颈动脉内-中膜厚度,根据颈动脉内-中膜厚度将164例患者分为颈动脉粥样硬化组和颈动脉内中膜正常组(对照组),测定2组血清尿酸和高敏C反应蛋白水平,并进行比较。结果:颈动脉粥样硬化组颈动脉内-中膜厚度、血清尿酸和高敏C反应蛋白水平均高于对照组(P<0.01)。结论:老年高血压患者颈动脉粥样硬化与血清尿酸和高敏C反应蛋白水平密切相关。
Objective: To investigate the relationship between serum uric acid and high-sensitivity C-reactive protein and carotid intima-media thickness in elderly patients with hypertension. Methods: The carotid artery intima - media thickness was measured in 164 elderly patients with essential hypertension. According to the carotid intima - media thickness, 164 patients were divided into carotid atherosclerosis group and normal carotid intima - media group Group), serum uric acid levels and high-sensitivity C-reactive protein levels were measured and compared. Results: The carotid intima - media thickness, serum uric acid and high sensitive C - reactive protein in carotid atherosclerosis group were higher than those in control group (P <0.01). Conclusion: Carotid atherosclerosis is closely related to serum uric acid and high-sensitivity C-reactive protein in elderly patients with hypertension.