论文部分内容阅读
作者用钳夹小鼠的坐骨神经的方法作为周围神经损伤的模型,并用补阳还五汤作为治疗药物与西药地巴唑、维生素 B_1作为对照,通过对小腿三头肌湿重,腓肠肌细胞直径的测量来说明补阳还五汤对小鼠坐骨神经的修复有促进作用。同时通过用血液流变学的检测来说明补阳还五汤的作用机理。可能是早期改善微循环,促进损伤局部炎性水肿的消退,后期可能与促进免疫功能有关。
The authors used the method of clamping the mouse’s sciatic nerve as a model of peripheral nerve injury, and used Buyang Huanwu Decoction as a therapeutic drug to control the western medicine debaazole and vitamin B_1 as the control, through the wet weight of the triceps brachii, and the diameter of the gastrocnemius muscle cells. Measurements have shown that Buyang Huanwu Decoction can promote the repair of sciatic nerve in mice. At the same time, the mechanism of action of Buyang Huanwu Decoction was demonstrated by testing with hemorheology. It may be the early improvement of microcirculation, the promotion of local inflammatory edema, and may be related to the promotion of immune function in the later period.