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【目的】探讨以发热为主要症状的儿童嗜肺军团菌感染临床特点。【方法】回顾性分析了5年中以不明原因发热收入住院最终确诊为嗜肺军团菌感染的77例患儿临床资料。【结果】60例诊断为嗜肺军团菌感染,14例为嗜肺军团菌肺炎,3例合并多器官功能障碍;除11例有轻微咳嗽外,其余病例无特异性症状;38例无任何阳性体征,4例患儿双肺闻及中细湿啰音,21例呼吸音粗;53例血常规白细胞在4~10×109/L内,2例<4×109/L,22例>10×109/L,36例CRP<10 mg/L,38例>10 mg/L;X线检查:双肺斑片影14例,双肺纹理稍粗21例,其余无异常。【结论】临床中遇不明原因持续发热的患儿,尤其是经青霉素类或头孢类抗生素治疗效果不佳的病例,除考虑常见的发热性疾病外,应警惕嗜肺军团菌感染可能。
【Objective】 To investigate the clinical characteristics of Legionella pneumophila infection in children with fever as the main symptom. 【Methods】 The clinical data of 77 children with Legionella pneumophila infection finally admitted to hospital with unknown cause fever for 5 years were retrospectively analyzed. 【Results】 60 cases were diagnosed as Legionella pneumophila infection, 14 cases were Legionella pneumophila pneumonia, 3 cases were complicated with multiple organ dysfunction. Except 11 cases with mild cough, the other cases had no specific symptoms and 38 cases had no positive There were 21 cases of breath sounds coarse in 4 cases, and 4 cases of blood routine white blood cells in 4 ~ 10 × 109 / L, 2 cases of <4 × 109 / L, 22 cases of> 10 × 109 / L, 36 cases of CRP <10 mg / L, 38 cases> 10 mg / L; X-ray examination: double lung lesions in 14 cases, lungs slightly thicker in 21 cases, the rest without exception. 【Conclusions】 In clinical cases, children with persistent unexplained fever, especially those with poor response to penicillin or cephalosporin antibiotics, should pay attention to the possibility of Legionella pneumophila infection besides the common febrile diseases.