子宫内膜容受性(ER)是胚胎着床的重要因素,薄型子宫内膜(thin endometrium)是导致ER差的原因之一。薄型子宫内膜的发病机制、内膜厚度及血流灌注都与其胚胎移植的成功率息息相关,因此薄型子宫内膜的治疗显得尤为重要。近年来的一些研究证实了粒细胞集落刺激因子(G-CSF)在子宫内膜修复方面起到了积极的促进作用,探讨总结粒细胞集落刺激因子对子宫内膜的修复机制对胚胎移植适应症及临床应用具有重要意义。 Endometrial receptivity (ER) is an important factor in embryo implantation, and thin endometrium is one of the causes of poor ER. The pathogenesis of thin endometrium, endometrial thickness and perfusion are closely related to the success rate of embryo transfer, so the treatment of thin endometrium is even more important. In recent years, some studies have confirmed that G-CSF plays a positive role in the repair of endometrium, to explore the mechanism of granulocyte colony stimulating factor on endometrial repair of embryo transfer indications and Clinical application is of great significance.