患者女性,1974年49岁时曾用氨苯砜治愈顽固性口疮性口炎。1978年因血性腹泻、肛周溃疡及体重减轻而入院,内镜及X线检查发现克隆氏病已累及末端回肠、升结肠及近端直肠后,经类固醇及柳氮磺胺吡啶治疗得到控制,但1982年因肠梗阻首次行肠切除,病理检查证实为肉芽肿性回肠结肠炎,标本切片未发现耐酸杆菌。 Female patient, 1974 years old with dapsone to cure stubborn aphthous stomatitis. In 1978 due to bloody diarrhea, perianal ulcer and weight loss and admission, endoscopic and X-ray examination found that Crohn’s disease has involved the terminal ileum, ascending colon and proximal rectum, steroids and sulfasalazine treatment control, but Bowel resection was performed for the first time in 1982 due to intestinal obstruction, and pathological examination was confirmed as granulomatous ileocolitis. No acid-fast bacilli were found in the specimen sections.