吡哌酮为选择性抗毒蕈碱剂,治疗消化性溃疡有效。每日服100～150mg,疗效与H_2受体阻滞剂相当。本文报道84例已愈合的十二指肠溃疡病人,接受本品50mg一日2次或安慰剂,进行为期1年的随机双盲多中心试验。试验期间对病人进行临床随访,并在治疗前及治疗3、6和12个月后做内窥镜检查,其中包括有溃疡复发症状2天以上者。对比两组病人年龄、性别、溃疡病时间和吸烟习惯,无明显差异。除资料不完整的 Piperonyl ketone is a selective anti-muscarinic agent, effective treatment of peptic ulcer. Daily service 100 ~ 150mg, efficacy and H 2 receptor blockers. This article reports 84 cases of duodenal ulcer patients who have healed, receiving the product 50mg twice daily or placebo for a one-year randomized double-blind multicenter trial. During the trial, patients were followed up and examined before treatment and 3, 6 and 12 months after treatment, including those with ulcer recurrence for more than 2 days. There was no significant difference between the two groups in age, sex, ulcer disease duration and smoking habit. In addition to incomplete information