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目的 :研究康莱特 (KLT)注射液对肝癌细胞化疗增敏作用。方法 :用癌细胞药物敏感性试验(MTT法 )测定KLT注射液和 5种化疗药联合作用的敏感度与对照组比较。结果 :KLT注射液联合化疗药的抑瘤率高于单纯化疗药 (P <0 0 5)。结论 :KLT注射液分别和 5 FU、CP、DDP、MMC联用比单纯化学药物治疗肝癌有明显的增敏作用。
Objective: To study the chemosensitization effect of KLT injection on hepatocellular carcinoma cells. METHODS: The sensitivity of the combined effect of KLT injection and five chemotherapeutic drugs was compared with that of the control group using the cancer cell drug sensitivity test (MTT method). Results: The inhibition rate of KLT injection combined with chemotherapy was higher than that of chemotherapy alone (P <0 05). Conclusion : KLT injection combined with 5 FU, CP, DDP, and MMC has significant sensitization effect compared with chemotherapy alone.