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应用聚合酶链反应(PCR)技术,对216例妊娠12~37周孕妇的宫颈阴道分泌物和其中109例孕妇分娩时的羊水进行解脲脲原体(UU)DNA检测,同时临床观察216例孕妇的妊娠结局。结果:宫颈阴道分泌物UUDNA阳性率为4306%,宫颈阴道UUDNA阳性组对应的羊水UU检出率明显高于阴性组(P<0005),两组平均孕周、平均出生体重、平均Apgar评分(1分钟)以及胎儿窘迫、早产、剖宫产、低出生体重儿、低Apgar评分和新生儿畸形的发生率无显著性差异(P>005),阳性组胎膜早破的发生率显著高于阴性组(P<0005)。提示:孕妇下生殖道UU感染与羊水UU感染和胎膜早破有关,而与胎儿窘迫、早产、剖宫产、低出生体重儿、新生儿窒息和新生儿畸形的发生无明显关系。
Polymerase chain reaction (PCR) was used to detect UU DNA in 216 cases of cervical vaginal secretions of pregnant women between the ages of 12 and 37 weeks and 109 cases of pregnant women during delivery. At the same time clinical observation of 216 cases Pregnancy outcome of pregnant women. Results: The positive rate of UUDNA in cervicovaginal secretions was 4306%, and the positive rate of UU in UUFNA positive cervical cervix was significantly higher than that in negative group (P <0005). The mean gestational age, mean birth weight, The average Apgar score (1 minute) and fetal distress, preterm birth, cesarean section, low birth weight children, low Apgar score and neonatal malformations no significant difference (P> 005), positive group premature rupture of membranes The incidence was significantly higher than the negative group (P <0005). It is suggested that UU infection of lower genital tract in pregnant women is related to UU of amniotic fluid and premature rupture of membranes, but not to fetal distress, premature birth, cesarean section, low birth weight, neonatal asphyxia and newborn malformation.