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目的：探讨宫颈癌组织中ＣＥＡ、ＰＣＮＡ表达与放疗预后的关系。方法：采用ＳＰ免疫组化方法检测３０例宫颈癌放疗前活检组织中ＣＥＡ、ＰＣＮＡ表达情况，并随访对照疗效。结果：ＣＥＡ、阳性率为８６．７％，五年生存组阳性率为８２．２％。ＰＣＮＡ高表达者五年生存组占７０．６％，死亡组占３８．５％，且均为Ⅲ期以上者。结论：ＣＥＡ在宫颈癌的表达与疗效无关。ＰＣＮＡ高表达者对放疗敏感，临床分期越早疗效越好。ＰＣＮＡ可做为判断宫颈癌放疗预后和指导治疗的一项指标。
Objective: To investigate the relationship between the expression of CEA and PCNA in cervical carcinoma and the prognosis of radiotherapy. Methods: SP immunohistochemical method was used to detect the expression of CEA and PCNA in 30 cases of cervical cancer biopsy before radiotherapy, and follow-up control efficacy. Results: The positive rate of CEA was 86.7% and the positive rate of five-year survival group was 82.2%. PCNA high expression of five-year survival group accounted for 70.6%, death group accounted for 38.5%, and are more than Ⅲ. Conclusion: The expression of CEA in cervical cancer has nothing to do with the curative effect. High expression of PCNA is sensitive to radiotherapy, the clinical stage of the better efficacy. PCNA can be used as a guide to determine the prognosis of cervical cancer radiotherapy and guidance.