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目的观察尿激酶联合低分子肝素钙治疗进展性脑梗死患者的临床疗效。方法将60例患者随机分为两组,对照组采用常规缺血性脑血管病治疗;治疗组采用小剂量尿激酶30万U溶于生理盐水100 ml,30 min滴完,1次/d,7 d为1个疗程,低分子肝素钙5000 U皮下注射,1次/d,10 d为1个疗程。结果治疗组患者治疗3周后基本治愈率、显著进步率均高于对照组。结论低分子肝素钙联合小剂量尿激酶治疗进展性脑梗死安全、有效。
Objective To observe the clinical effect of urokinase combined with low molecular weight heparin on patients with progressive cerebral infarction. Methods Sixty patients were randomly divided into two groups. The control group was treated with conventional ischemic cerebrovascular disease. The treatment group was treated with 30 000 U of low-dose urokinase in 100 ml normal saline for 30 min, once / d, 7 d for a course of treatment, low molecular weight heparin 5000 U subcutaneous injection, 1 / d, 10 d for a course of treatment. Results After treatment for 3 weeks, the basic cure rate and the significant improvement rate in the treatment group were higher than those in the control group. Conclusions Low molecular weight heparin combined with low dose of urokinase is safe and effective in the treatment of advanced cerebral infarction.