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本文目的在于分析和评价长期接触二氧化硅粉尘工人,其中包括矽肺病人支气管肺泡冲洗液(BAL)中细胞成分的临床意义。作者检查了50名有矽肺危险职业的工人(清整工、翻砂工、型芯工),年龄35～56岁。第1组是19名在游离二氧化硅含量大于10%的高浓度粉尘条件下工作17±1.8年的工人,第2组是31名没有合并症的Ⅰ期矽肺病人,平均接尘工龄20.5±1.23年。矽肺病人又分成两个亚组:2A组19名工人是在本次受检时新确诊的Ⅰ期矽肺,2B组12名工人确诊矽肺的平均时间已达6年。所有工人,除进行一般检查外,按常规方法通过纤维支气管镜抽取BAL,过滤后1500r/min离心15min,取沉淀做细胞计数后涂片做细胞学研究,Папенгейм—Крюков法染色,光镜下计数不少于500个细胞,结果见附表。
The purpose of this paper is to analyze and evaluate the clinical implications of long-term exposure to silica dust workers, including cellular constituents in bronchoalveolar lavage fluid (BAL) in patients with silicosis. The authors examined 50 workers at risk of silicosis (cleaners, sand-turning workers, and core workers) aged 35- 56 years. The first group consisted of 19 workers working for 17 ± 1.8 years with high concentrations of dust containing more than 10% free silica. The second group consisted of 31 patients with stage I silicosis who had no comorbidity. The average age of workers exposed to dust was 20.5 ± 1.23 years. Silicosis patients were divided into two subgroups: 19 workers in group 2A were newly diagnosed stage I silicosis at this examination, and the average time for diagnosing silicosis in 12 workers in group 2B was 6 years. All workers, in addition to the general examination, according to the conventional method by bronchoscopy BAL, after centrifugation at 1500r / min for 15min, the sediment to do cell counting cytology after smear cytology, staining, counting under light microscopy Not less than 500 cells, the results see Schedule.