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本文报告应用放射免疫法测定139例寻常型银屑病患者血清β_2-m水平。结果:病人总体的血清β_2-m水平有明显的升高,与正常对照组比较差异有显著性(P<0.01)。并与病情严重性有明显的关系,如病损面积超过10%比小于10%者与正常对照组比较,差异更为明显(P<0.01)。病型、病程与正常对照组比较也有明显差异(P<0.01)。进行期、静止期与正常组比较,有明显差异(P<0.01),而消退期则无意义(P>0.05)。我们还将各病组间自身血清β_2-m含量做对比,发现差异均有显著性(P<0.01)。我们认为,血清β_2-m
This article reports the application of radioimmunoassay determination of 139 cases of patients with psoriasis serum β 2-m levels. Results: The serum level of β_2-m in patients was significantly higher than that in normal controls (P <0.01). There was a clear relationship between the severity of the disease and the severity of the disease. If the lesion area was more than 10% and less than 10%, the difference was more significant (P <0.01) than the normal control group. The disease type and course of disease were also significantly different from the normal control group (P <0.01). There was a significant difference between normal group and quiescent group (P <0.01), while there was no significant difference between the two groups (P> 0.05). We also compare the serum levels of β_2-m between the various disease groups and found significant differences (P <0.01). We think that serum β_2-m