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目的探讨颅内非松果体区生殖细胞瘤的临床特点和治疗方法。方法８例颅内非松果体区生殖细胞瘤均经手术病理证实，其中鞍区６例，基底节区２例。位于鞍区者以尿崩症为主要临床表现，位于基底节区者以偏侧肢体障碍多见。显微镜下次全切除２例，大部分切除５例，部分切除１例，术后７例行常规放疗。结果临床症状改善５例，无变化２例，１例死于急性丘脑下部损伤。结论颅内非松果体区生殖细胞瘤的诊断主要依据临床表现和ＣＴ、ＭＲＩ影像学特征。手术切除困难，术后正规放疗效果好，是提高疗效的重要措施
Objective To investigate the clinical features and treatment of intracranial non-pineal region germinoma. Methods Eight cases of intracranial non-pineal region germ cell tumors were confirmed by surgery and pathology, including 6 cases of saddle and 2 cases of basal ganglia. People who are located in the saddle area have diabetes insipidus as the main clinical manifestations. Those who are located in the basal ganglia are more common in unilateral limb disorders. Microscopically the next total resection in 2 cases, the majority of resection in 5 cases, partial resection in 1 case, 7 cases after conventional radiotherapy. Results Clinical symptoms improved in 5 cases, no change in 2 cases, 1 case died of acute hypothalamic injury. Conclusion The diagnosis of intracranial non-pineal region germinoma mainly based on clinical manifestations and CT, MRI imaging features. Difficult surgical resection, regular radiotherapy effect is good, is to improve the efficacy of important measures