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目的探讨成都城乡地区中老年人群LDLC升高的流行状况及影响因素,为今后本地区脂代谢异常防治奠定基础。方法样本的获取采用分层整群抽样的方法,以社区(村)为单位,抽取城乡社区40~79岁有代表性人群5 230人进行LDLC及相关因素的调查。结果成都地区中老年人群LDLC升高的患病率2.18%。标化患病率为2.03%。40~74岁人群随年龄增大LDLC升高的患病率逐渐增高;75岁以后患病率略有下降。男女两性及城乡患病率差异均无显著性(P均>0.05)。成都地区中老年男性人群LDLC升高的危险因素为年龄、糖尿病,适度饮酒为保护因素;中老年女性人群LDLC升高的危险因素为分娩巨大儿、腹型肥胖、糖尿病,保护因素为适度饮酒、体力锻炼。结论成都地区中老年人群LDLC升高的患病率较低,明显低于全国水平。成都乃至四川地区冠心病的相对低发可能与人群高LDLC血症的低患病率有关。防治糖尿病、适度饮酒、合理体力锻炼对预防LDLC升高可能有积极意义。
Objective To investigate the prevalence and influencing factors of elevated LDLC in middle-aged and elderly population in urban and rural areas in Chengdu, and to lay the foundation for the prevention and treatment of abnormal lipid metabolism in the future. Methods The samples were obtained by stratified cluster sampling method. The community (village) as a unit, 5,230 representative population aged 40-79 years in urban and rural communities were collected for LDLC and related factors. Results The prevalence of elevated LDLC in middle-aged and elderly people in Chengdu was 2.18%. The standardized prevalence was 2.03%. The prevalence of LDLC increased with age in 40-74 years old group; The prevalence after 75 years old decreased slightly. There was no significant difference between male and female and the prevalence of urban and rural areas (P> 0.05). The risk factors of LDLC in middle-aged and elderly men in Chengdu are age, diabetes and moderate alcohol consumption. The risk factors for LDLC in middle-aged and elderly women are childbearing gigantism, abdominal obesity and diabetes. The protective factors are moderate alcohol consumption, Physical exercise. Conclusion The prevalence of elevated LDLC in middle-aged and elderly people in Chengdu is lower than that of the whole country. The relative low incidence of coronary heart disease in Chengdu and Sichuan may be related to the low prevalence of high LDLC in the population. Prevention and treatment of diabetes, moderate drinking, physical exercise reasonable to prevent the rise of LDLC may have positive significance.