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目的探讨美托洛尔联合稳心颗粒治疗心律失常患者的临床疗效。方法选取2012年10月至2015年6月微山县中医院收治的124例心律失常患者作为研究对象,按随机数字表法将其分为对照组和试验组,每组62例。对照组患者口服稳心颗粒,试验组患者在对照组基础上采用美托洛尔进行治疗,比较两组患者动态心电图检测结果、治疗效果及不良反应发生情况。结果治疗后,试验组患者的室性早搏发生频率明显低于对照组,ST段压低及ST段压低持续时间均明显短于对照组,差异均有统计学意义(均P<0.05);试验组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05)。结论美托洛尔联合稳心颗粒治疗心律失常的临床疗效优于单纯使用稳心颗粒,能有效改善心脏功能,且安全性高。
Objective To investigate the clinical efficacy of metoprolol combined with Wenxin Keli in the treatment of patients with arrhythmia. Methods A total of 124 patients with arrhythmia admitted to Weishan County Hospital of Traditional Chinese Medicine from October 2012 to June 2015 were selected as study subjects and divided into control group and trial group according to random number table method, with 62 cases in each group. Patients in the control group were given oral Wenxin Granules. Patients in the test group were treated with metoprolol on the basis of the control group. The results of Holter test, treatment effect and adverse reactions were compared between the two groups. Results After treatment, the incidence of ventricular premature beats in the experimental group was significantly lower than that in the control group. The ST-segment depression and ST-segment depression duration were significantly shorter than those in the control group (all P <0.05) The total effective rate of patients treated was significantly higher than the control group, the difference was statistically significant (P <0.05). Conclusion Metoprolol combined with Wenxin Granule in treating arrhythmia has better clinical efficacy than using Wenxin Granule alone, which can effectively improve cardiac function and is safe.