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目的探讨奥美拉唑治疗消化性溃疡患儿的临床效果。方法选取2013年3月至2015年2月辽宁省本溪钢铁集团(有限)公司总医院收治的88例消化性溃疡患儿作为研究对象,按随机数字表法将其分为观察组和对照组,各44例。对照组患儿给予常规治疗,观察组患儿在对照组基础上采用奥美拉唑进行治疗,比较两组患儿的临床疗效、Hp清除率、疼痛缓解时间及不良反应发生情况。结果观察组患儿治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患儿的Hp清除率明显高于对照组,差异有统计学意义(P<0.05)。结论奥美拉唑是一种治疗小儿消化性溃疡的有效药物,可以提高三联疗法的效果,安全性较高,还能有效清除HP,减少复发。
Objective To investigate the clinical effect of omeprazole in children with peptic ulcer. Methods Eighty-eight children with peptic ulcer admitted to the General Hospital of Benxi Iron and Steel (Group) Co., Ltd. from March 2013 to February 2015 in Liaoning Province were selected as study subjects and divided into observation group and control group according to random number table method. 44 cases each. Children in the control group were given routine treatment. The children in the observation group were treated with omeprazole on the basis of the control group. The clinical efficacy, Hp clearance rate, pain relief time and adverse reactions of the two groups were compared. Results The total effective rate of treatment group was significantly higher than that of control group, the difference was statistically significant (P <0.05); Hp clearance rate of observation group was significantly higher than that of control group, the difference was statistically significant (P <0.05 ). Conclusion Omeprazole is an effective drug for the treatment of peptic ulcer in children. It can improve the effect of triple therapy and has higher safety. It can also effectively remove HP and reduce recurrence.