目的:探讨30岁以下青年乳腺癌的病理特点,并对影响其预后的相关因素进行分析。方法:回顾性分析1989年12月～2000年12月收治的102例30岁以下乳腺癌患者的临床病理资料,观察患者长期无瘤生存率,分析放射治疗临床特点及影响预后的因素。结果:病理类型中浸润性癌占多数,高达98.99%,3年无瘤生存率为86.73%,5年无瘤生存率为72.47%。Ⅳ期5年无瘤生存率显著低于其他分期者。肿瘤直径≤3cm和>3cm的患者其5年无瘤生存率分别为75.00%、62.96%(P<0.05)。腋窝淋巴结转移阴性者3年、5年无瘤生存率分别为92.11%、81.58%,1～3枚阳性者3年、5年无瘤生存率分别为88.24%、70.59%,≥4枚阳性者3年、5年无瘤生存率分别为84.00%、40.00%。放射治疗组3年、5年无瘤生存率分别为94.44%和90.28%,未行放射治疗组3年、5年无瘤生存率分别为76.67%和15.62%(P<0.05)。结论:对于青年乳腺癌患者,需早期诊断,早期规范性治疗,以提高无瘤生存率,降低复发率。 Objective: To investigate the pathological features of breast cancer in young people under 30 years old, and to analyze the related factors that affect their prognosis. Methods: The clinical and pathological data of 102 patients with breast cancer under 30 years of age who were treated from December 1989 to December 2000 were retrospectively analyzed. The long-term disease-free survival rate was observed. The clinical features of radiotherapy and prognostic factors were analyzed. Results: The most common pathological types of invasive carcinoma were as high as 98.99%. The 3-year disease-free survival rate was 86.73%. The 5-year disease-free survival rate was 72.47%. 5-year disease-free survival rate was significantly lower than other stages. The 5-year disease-free survival rates were 75.00% and 62.96%, respectively (P <0.05) in patients with tumors ≤3 cm and> 3 cm. The 3-year, 5-year, and 5-year disease-free survival rates were 92.11% and 81.58% respectively. The 3-year survival rates of 1 to 3 positive patients were 88.24%, 70.59% and ≥4, respectively Three years, 5-year disease-free survival rates were 84.00%, 40.00%. The 3-year, 5-year disease-free survival rates of radiotherapy group were 94.44% and 90.28%, respectively. The 5-year disease-free survival rates of radiotherapy group were 76.67% and 15.62% respectively (P <0.05). Conclusion: For young patients with breast cancer, early diagnosis and early normative treatment are needed to improve the disease-free survival rate and reduce the recurrence rate.