巨噬细胞在机体中分布广泛并具有十分活跃的生物学功能,如吞噬清除病原体,提呈抗原等,在机体防御和免疫应答中发挥着重要作用。近年来,对巨噬细胞主要着重于其异质性的研究,即其在受到细菌或寄生虫感染时会分别分化成两个不同的亚群:M1和M2。其中M1型巨噬细胞具有清除病原体与 Macrophages are widely distributed in the body and have very active biological functions, such as phagocytizing and removing pathogens, presenting antigens and playing an important role in body defense and immune response. In recent years, macrophages have focused primarily on their heterogeneity in that they differentiate into two distinct subgroups, M1 and M2, respectively, upon infection by bacteria or parasites. M1 macrophages which have clear pathogen and