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观察保尔佳对癌症患者的辅助疗效。１９９５年８月～１９９６年５月，６０例癌症放疗患者随机分成两组：采用保尔佳联合放疗的综合组和单用放疗的对照组。两组放射剂量范围５４～７１．２Ｇｙ／６～７．５周。治疗前后对患者的全身情况、症状变化进行评价，并检测患者的外周血白细胞、淋巴细胞、Ｔ细胞亚群、ＮＫ细胞和ＩＬ－２Ｒ，肿瘤治疗结果在疗后２个月进行评价。对照组放疗后全身情况明显下降（Ｐ＜０．０５），综合组未见明显下降；疼痛缓解率综合组和对照组分别为８／１２和４／１０；对照组患者放疗后外周血白细胞、淋巴细胞和ＮＫ细胞明显下降（Ｐ＜０．０１），综合组仅淋巴细胞下降（Ｐ＜０．０５），其余无明显变化（Ｐ＞０．０５）；综合组ＣＤ３＋、ＣＤ４＋、ＣＤ４＋／ＣＤ８＋比值明显上升（Ｐ＜０．０５～０．０１），对照组变化不明显；综合组ＩＬ－２Ｒ明显下降（Ｐ＜０．０５），对照组未见明显变化，带瘤患者肿瘤消退有效率（ＣＲ＋ＰＲ）综合组为１００％（１７／１７），对照组为８３．３％（１５／１８）。保尔佳有较强的抗肿瘤，改善症状和提高机体免疫水平的作用，能减轻放疗的副作用，具有良好的辅助疗效，为癌症的综合治疗提供了一种新药。
Observe the adjuvant efficacy of Pulcan for cancer patients. From August 1995 to May 1996, 60 patients with cancer radiotherapy were randomly divided into two groups: a comprehensive group with Pulgar combined radiotherapy and a control group with radiotherapy alone. The radiation dose range of the two groups was 54 to 71.2 Gy/6 to 7.5 weeks. Before and after treatment, the patient’s general condition and symptom changes were evaluated. Peripheral white blood cells, lymphocytes, T cell subsets, NK cells, and IL-2R were detected. Tumor treatment results were evaluated 2 months after treatment. After the radiotherapy in the control group, the general condition was significantly decreased (P<0.05). There was no significant decline in the comprehensive group; the pain relief rate in the comprehensive group and the control group was 8/12 and 4/10, respectively; the control group had peripheral blood leukocytes after radiotherapy. Lymphocytes and NK cells decreased significantly (P<0.01). In the comprehensive group, only lymphocytes decreased (P<0.05), while the rest did not change significantly (P>0.05); comprehensive group CD3+, CD4+, CD4+/CD8+ The ratio increased significantly (P<0.05-0.01), but there was no significant change in the control group; IL-2R in the comprehensive group decreased significantly (P<0.05). There was no significant change in the control group. Tumor regression was effective in tumor patients. (CR+PR) was 100% (17/17) in the comprehensive group and 83.3% (15/18) in the control group. Bao Jia Jia has a strong anti-tumor, improve symptoms and improve the body’s immune level, can reduce the side effects of radiotherapy, has a good adjuvant effect, for the comprehensive treatment of cancer provides a new drug.